Dejerine’s
Sign
Clinical Pearl
Patients with radicular symptoms and pronounced Dejerine’s
sign, especially if it is in the lumbar spine, should be told to bend the knees
and lean into a wall during a cough or sneeze. This maneuver reduces
intradiscal pressure and minimizes the effect of the cough or sneeze on the
nerve root. A more worrisome situation is the sudden, unexpected absence of
Dejerine’s sign when all other clinical findings indicate an active nerve root
compression. The loss of the sign indicates fragmentation of the disc with
momentary decompression of the nerve.